Peter Hoffmann is a brilliant young mathematician and physicist who teaches materials science at Wayne University, yet he and his enlightening book "Life's Ratchet", and not a biologist, that which is, at present, probably the finest representation of a cell: the cell like a city. In this metaphor the cell membrane can be seen as the city wall built in malta (phospholipids) and brick (cholesterol), where there are several doors (membrane receptors) and several customs points (transporters) which impose duties in coin (ATP) which reflects the need of good in transit from the city-cell). In this city there are several factories (Ribosomes) that produce all manner of goods (proteins) that are transported to all parts of the city thanks to very efficient truck (dynein and kinesin-like proteins) that run on a dense motorway network (the cytoskeleton). All traffic of goods is governed by the Central Post Office (Golgi apparatus) that receives requests and directs everything to the right location. In this industrious city has no shortage of power plants that produce energy for all its activities (mitochondria) and landfills to ensure hygiene and urban décor (Lysosomes). Some cities are full of parks and public green (chloroplasts), now no longer see a leaf. The most important and sacred place of each city is however its municipal library (the nucleus), which contained all the knowledge, culture and traditions of that city, in other words its history and know that read, probably his future.
La metabolomica è una delle scienze che realizza al meglio questo approccio alla ricerca dei meccanismi di relazione gene-ambiente.
Il kit MetaboPrep può essere visto come una sorta di tour operator che organizza un viaggio conoscitivo all’interno di una città consentendo di visitare tutti i luoghi chiave e di parlare con tutte le persone che possano raccontarvi il necessario per conoscere quella città. Inoltre vi consentirà, per mezzo di un praticissimo diario di viaggio, di costruire un’immagine unica della città che conserverete indelebilmente nel vostro archivio dei ricordi.