Projects

MAMA Test

Theoreo srl has developed a non-invasive diagnostic test for prenatal diagnosis (NIPD). This test is called M.A.MA Test (Metabolomics Approach for MAlformation) and is based on bioinformatic analysis, by means of classification models and machine learning of the Metabolome retrieved from a single drop of maternal blood. It is therefore a non-invasive method and safe for mother and fetus. This test is currently patent pending and Theoreo srl is conducting a trial to validate the test according to the strictest international standards.             

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MEDEA TEST

Theoreo srl is also active in Oncology. it has developed a diagnostic test for the diagnosis of endometrial carcinoma, one of the most fearsome cancers that affect women. This test is patent pending and will be subjected to a clinical trial in order to be validated according to the strictest international standards.

CD-GEMM


Theoreo represents the last M of the CD-GEMM project (Celiac Disease - Genetic Environmental Microbiome and Metabolomic Study).
With CD-GEMM we plan to follow the evolution of the intestinal microbiota in children at risk of developing celiac disease.
Objectives of the study are:
A) Study prospectively the changes in the microbiota and faecal metabolome in relation to the maternal fecal microbiota and the infant feeding pattern (breastfeeding, artificial feeding, introduction of complementary feeding).
B) To study blood levels of zonulin in relation to age, infant feeding methods and intestinal microbiota.
C) Identify any environmental factors (infections, use of antibiotics, number of cohabitants in the family, presence of domestic animals) associated with the development of celiac disease (assessed in terms of positivization of anti-transglutaminase anti-IgG and anti-gliadin IgA and IgG ).

GEMMA

Theoreo srl has developed a non-invasive diagnostic test for prenatal diagnosis (NIPD). This test is called M.A.MA Test (Metabolomics Approach for MAlformation) and is based on bioinformatic analysis, by means of classification models and machine learning of the Metabolome retrieved from a single drop of maternal blood. It is therefore a non-invasive method and safe for mother and fetus. This test is currently patent pending and Theoreo srl is conducting a trial to validate the test according to the strictest international standards.             

Details...